ANALYSIS OF PARB-CENTROMERE INTERACTIONS BY MULTIPLEX SPR IMAGING REVEALS SPECIFIC PATTERNS FOR BINDING PARB IN SIX CENTROMERES OF BURKHOLDERIALES CHROMOSOMES AND PLASMIDS.

Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids.The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons.Closely related f

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Lying To Our Children

Most parents lie to their children.They do it for fun, as a method of behaviour control, and to protect children from what they consider to be dangerous truths.At the same time, most parents bring their children up with the message that honesty is a virtue and that lying is usually wrong.How should our practice and our preaching be reconciled? In t

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